Semaglutide and tirzepatide is a once-weekly medication in its class to help with chronic weight management. It works best when used in combination with a healthy diet and exercise. Either injections are given weekly subcutaneously in the fat of the thigh, stomach or arm. It works for weight loss as an appetite suppressant, helping to control cravings and portion control.
Phentermine is an appetite suppressant used in combination with diet and exercise to achieve successful weight management. It is designed for short-term use, often helpful for patients who find themselves stuck in a plateau. Phentermine, a FDA approved appetite suppressant, has been used since 1959 to aid in medical weight loss. Doctors often use Phentermine before resorting to surgical intervention, due to its proven safety and efficiency. This drug has an extremely low addiction and dependence potential, therefore classifying it as a Schedule IV.
Working on the hypothalamus portion of the brain, phentermine stimulates the adrenal glands to release norepinephrine. This sends a chemical message to the brain that signals a fight response and in turn reduces hunger. Phentermine also releases adrenaline which causes fat cells to break down stored fat. The metabolism of phentermine like many other medications takes place in the liver.
Phentermine should not be taken during pregnancy, if attempting pregnancy or while breastfeeding. Patients should avoid using phentermine if taking stimulants such as Adderall, Ritalin, or on a MAOI Inhibitor. Those with Hyperthyroidism, Glaucoma, Peptic Ulcer Disease, Prostatic Hypertrophy, Cardiac Disease, or Epilepsy should avoid taking Phentermine as well. Alcohol should be avoided when taking phentermine. If alcohol consumption will occur, avoid taking your daily dose and resume the following day.
The most common side effects associated with Phentermine are dry mouth, nervousness, restlessness, and constipation. Many of the side effects can be avoided by increasing water consumption and avoiding caffeine.
Anyone whose BMI is greater than 30 may benefit from prescription phentermine. Those with a BMI greater than 25, with an increased weight related risk or diagnosed with a weight related medical condition, may also benefit.